Johnny Millar

Clinician-Scientist | Co-Founder, Multiscale Labs

Portrait image of Johnny Millar

I'm Johnny Millar, a clinician-scientist working at the intersection of artificial intelligence and biology. Currently, I am a Senior Research and Generative AI Lab Fellow at the University of Edinburgh. Alongside my research work, I'm privileged to care for patients as an Honorary Consultant in Intensive Care Medicine at Glasgow's Queen Elizabeth University Hospital. Most recently, I co-founded Multiscale Labs, a company that is building a platform for AI-driven drug discovery. Feel free to explore some of my endeavors at GitHub or follow me on LinkedIn.

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Projects

Functional Representation of Gene Signatures Embeddings Generator

A streamlit app to codelessly generate gene signature embeddings based on FRoGS (Nat. Commun. 2024).

ARDSMAICR

The ARDSMAICR package contains the results of a meta-analysis by information content (MAIC) of genome-wide studies of the host response to acute respiratory distress syndrome (ARDS). These data are accompanied by a range of helper functions useful for analysis.

Pubmed Command Line Interface

A Python cli that allows you to search PubMed for publications based on a specific query term.
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Selected Publications

GWAS and meta-analyses identifies 49 genetic variants underlying critical COVID-19.

Pairo-Castineira E, Rawlik K, Bretherick AD, ..., Millar JE, ..., Baillie JK.

Nature (2023)

DOI: 10.1038/s41586-023-06034-3

Whole genome sequencing reveals host factors underlying critical COVID-19.

Kousathanas A, Pairo-Castineira E, Rawlik K, ..., Millar JE, ..., Baillie JK.

Nature (2022)

DOI: 10.1038/s41586-022-04576-6

Effect of lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal vs standard care ventilation on 90-day mortality in patients with acute hypoxemic respiratory failure: the REST randomized trial.

McNamee JJ, Gillies MA, Barrett NA, ..., Millar JE, ..., McAuley DF.

JAMA (2021)

DOI: 10.1001/jama.2021.13374

Genetic mechanisms of critical illness in COVID-19.

Pairo-Castineira E, Clohisey S, Klaric L, ..., Millar JE, ..., Baillie JK.

Nature (2021)

DOI: 10.1038/s41586-020-03065-y

Combined mesenchymal stromal cell therapy and ECMO in ARDS: a randomised controlled trial in sheep.

Millar JE, Bartnikowski N, Passmore MR, et. al.

Am. J. Respir. Crit. Care Med. (2020)

DOI: 10.1164/rccm.201911-2143OC
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